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These discrepancies may be explained in part by the fact that while in most systems versions of CSD mimic the effects of endogenous CAV-1, in some systems they act as competitors of the activity of endogenous CAV-1 31,32,34,35,36

Neurobiol Aging 36(1):476484

Inflammatory and cell-mediated immune biomarkers in myalgic encephalomyelitis/chronic fatigue syndrome and depression: inflammatory markers are higher in myalgic encephalomyelitis/chronic fatigue syndrome than in depression

It depends on what you mean by targeted. For gut-focused support, capsules may feel more targeted because they pass through the digestive tract

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